sackler school

Hyperlipidemia, Caused by a High-Fat Diet, Aggressively Accelerates Organ Rejection

BOSTON (June 16, 2015, 12:01 a.m. EDT)—In two studies published online today in the American Journal of Transplantation, researchers determined that hyperlipidemia accelerates heart-transplant rejection in mice. By using models that mimic the health conditions found in human transplant recipients, the researchers from Tufts determined that transplant rejection was accelerated whether the hyperlipidemia (high cholesterol and high triglycerides in the blood) was caused by genetics or solely by a high-fat diet.